25-hydroxyvitamin D levels and bone histomorphometry in hemodialysis renal osteodystrophy

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Renal osteodystrophy in hemodialysis patients.

Patterns of bone loss in the axial and appendicular skeleton were studied in 88 chronic hemodialysis patients (59 males and 29 females) and 60 normal volunteers (30 males and 30 females). The hemodialysis patients were properly medicated with phosphate binders and 1 alpha-OH D3 where necessary. The metacarpal index (MCI), sigma gray scale/diameter (sigma GS/D) and bone mineral content (BMC) wer...

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Low 25-hydroxyvitamin D levels and cognitive impairment in hemodialysis patients.

BACKGROUND AND OBJECTIVES 25-hydroxyvitamin D (25[OH]D) deficiency and cognitive impairment are both prevalent in hemodialysis patients in the United States. This study tested the hypothesis that 25(OH)D deficiency may be associated with cognitive impairment because of its vasculoprotective, neuroprotective, and immune-modulatory properties. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This ...

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Renal function and 25-hydroxyvitamin D concentrations predict parathyroid hormone levels in renal transplant patients.

BACKGROUND Recent guidelines suggest supplementation with ergocalciferol (vitamin D(2)) in chronic kidney disease stages 3 and 4 patients with elevated parathyroid hormone (PTH) levels and 25-hydroxyvitamin D (25OHD) levels <75 nmol/l. These guidelines are also applied to renal transplant patients. However, the prevalence rates of 25OHD deficiency and its association with PTH levels in renal tr...

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Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels.

We determined the free fraction of 25-dihydroxyvitamin D (25OHD) in the serum of subjects with clinical evidence of liver disease and correlated these measurements to the levels of vitamin D binding protein and albumin. These subjects when compared to normal individuals had lower total 25OHD levels, higher percent free 25OHD levels, but equivalent free 25OHD levels. These subjects also had redu...

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Correlation of serum magnesium with serum levels of 25-hydroxyvitamin D in hemodialysis patients

Introduction 25-hydroxyvitamin D (25-OH vitamin D) is the main circulating metabolite of vitamin D (1). While the biological active form of vitamin D is 1,25(OH)2 vitamin D, synthesized in the kidney, it is broadly accepted that the measurement of circulating 25(OH) vitamin D offers better evidence with respect to the patients’ vitamin D status (1,2). Recently, various studies have shown the ro...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2005

ISSN: 0085-2538

DOI: 10.1111/j.1523-1755.2005.00603.x